THYMOSIN ALPHA 1.6 mg (Guficin) Injection

Uses of Thymosin Alpha

• Chronic hepatitis B where locally approved
• Chronic hepatitis C combination treatment in some countries
• Other specialist-directed immune-modulating uses

Benefits of Thymosin Alpha

• May support T-cell responses
• Helps regulate immune activity
• May support hepatitis treatment where approved

How Does Thymosin Alpha Work?

Thymosin alpha 1 is an immune-modulating peptide that influences the development and activity of T lymphocytes. It may also support dendritic cells, natural killer cells and other immune responses. Its clinical role and approved indications differ between countries.

Possible Side Effects

• Injection-site discomfort
• Redness
• Fatigue
• Fever
• Muscle or joint discomfort

Precautions

• Confirm that the intended use is locally approved.
• It must not replace established antiviral treatment.
• Use cautiously with autoimmune disease or transplantation.
• Discuss pregnancy and breastfeeding.
• Do not promote it as an established cancer or COVID-19 treatment.

Thymosin Alpha-1 Regulatory and Medicine Information by Country

Thymosin alpha-1 authorization, indications, availability and pricing vary substantially between countries. Major national databases may not provide a public price or reimbursement listing. The following resources provide regulatory and clinical background information.

• Review published clinical and regulatory background information on PubMed Central – https://pmc.ncbi.nlm.nih.gov/articles/PMC7747025/
• Review published Thymosin Alpha-1 medicine information in the World Journal of Gastroenterology – https://www.wjgnet.com/2220-3249/full/v9/i5/67.htm
• Review a scientific overview of Thymosin Alpha-1 in Molecules – https://www.mdpi.com/1420-3049/28/8/3539